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HPLC columns Product List

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Affordable HPLC Column Roc

A conventional budget HPLC column that combines reliable performance, exceptional value, and compact storage.

A conventional HPLC column designed to become a staple in the lab. Compatible with HPLC systems with a pressure tolerance of 400 bar (40 MPa). • Robustness and reliability—achieves the required peak shape, reproducibility, robustness, and performance. • Delivers exceptional value for routine analyses and large volumes of analysis—various stationary phases made from high-purity all-porous silica backed by stringent quality control, suitable for most HPLC methods. • Ideal for a wide range of applications from food to pharmaceuticals. Five types of stationary phases can cover 98% of USP methods. • Newly designed compact packaging for minimal storage—download the analysis certificate corresponding to the serial number at www.restek.com/documentation. Use Restek's Roc LC column to increase what you need and reduce what you don't. For more details, visit www.restek.com/roc.

  • Company:Restek
  • Price:10,000 yen-100,000 yen
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Ascentis Express HILIC Guide

Retention and separation of hydrophilic compounds made faster! Choose the right column for your needs with the HILIC stationary phase selection guide.

This document provides an explanation of HILIC and features various types of HILIC stationary phase columns. HILIC technology, which has complementary properties to both reverse phase (RP) and normal phase (NP) chromatography, is often used in studies analyzing hydrophilic analytes. Additionally, we offer a lineup of products including the "Ascentis Express OH5 HPLC column," "Ascentis Express ES-Cyano HPLC column," and others. We invite you to read through it. [Contents (excerpt)] ■ Ascentis Express U/HPLC columns ■ What is HILIC and reasons to choose it ■ Development of HILIC methods ■ Ascentis Express OH5 HPLC column *For more details, please refer to the PDF document or feel free to contact us.

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HPLC column for sugar analysis - "CarboSep Series"

Concise Separations manufactured high-speed liquid chromatography (HPLC) column for sugar analysis.

The CarboSep series from Concise Separations (formerly Transgenomic) is a column for sugar analysis in HPLC. You can choose the most suitable column for your samples from a wide range of products.

  • Separation and Analysis Equipment
  • HPLC columns

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[Application Note] HPLC Products for mRNA Analysis and Purification

By using the RNASep series from ADS Biotec in the United States, you can perform HPLC analysis and purification of mRNA.

By using the RNASep series HPLC columns from ADS Biotec in the United States and TEAA buffer, you can analyze and purify mRNA. The column beads are made of alkylated polystyrene-divinylbenzene, allowing for repeated use by cleaning the column. They are compatible with many HPLC systems. A key strength is the ability to analyze and purify long-chain mRNA up to 6K. Customers around the world utilize this product, and it boasts a significant number of publications.

  • High Performance Liquid Chromatograph
  • HPLC columns

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Application Note: HPLC Products for Oligonucleotide Analysis

HPLC column and buffer for oligonucleotide analysis

The HPLC columns and buffers for oligonucleotide analysis manufactured by ADS Biotec in the United States use beads made of alkylated polystyrene-divinylbenzene. The columns are referred to as the OligoSep series. Oligonucleotides are used in research for antisense and siRNA pharmaceuticals.

  • High Performance Liquid Chromatograph
  • HPLC columns

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Roc C8 HPLC column (USP L7)

Solid high reliability – provides the peak shape, reproducibility, robustness, and separation performance desired by users.

The Roc C8 HPLC column (USP L7) is designed to become a "standard" in LC analysis laboratories. These robust and highly reliable columns are compatible with HPLC systems that can withstand pressures up to 40 MPa, providing users with the desired peak shape, reproducibility, robustness, and separation performance for all LC applications. Their exceptional utility maximizes operational efficiency. The minimal package design allows for compact storage. 【Features】 ■ Designed to be a "standard" in LC analysis laboratories, this standard HPLC column is compatible with HPLC systems that can withstand pressures up to 40 MPa. ■ Solid high reliability – provides users with the desired peak shape, reproducibility, robustness, and separation performance. ■ Exceptional utility capable of handling a large volume of analytical tasks – diverse packing materials using high-purity silica backed by high-quality manufacturing processes are suitable for most HPLC methods. *This catalog is in English. *For more details, please download the PDF or contact us.

  • Contract manufacturing
  • HPLC columns

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[Application Example] HPLC Analysis of Organic Acids Using the Coregel Series

You can choose the optimal column from a rich lineup.

The Coregel series from Concise Separations in the United States is a column for the analysis of organic acids. This page contains application notes for the Coregel series.

  • High Performance Liquid Chromatograph
  • HPLC columns

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HPLC column for oligonucleotide HPLC purification - OligoSep Prep HC Cartridge

High-performance liquid chromatography (HPLC) column for the purification of synthetic oligonucleotides.

The OligoSep Prep HC Cartridge manufactured by ADS Biotec (formerly Transgenomic) is a column for the purification of oligonucleotides using ion-pair reverse phase HPLC. It uses porous beads made of alkylated polystyrene-divinylbenzene (PS-DVB). Due to the porous nature of the beads, the surface area is increased, allowing for the purification of larger amounts of samples. It can be used for the purification of synthetic oligos. It is compatible with various types of high-performance liquid chromatography (HPLC) systems. By using ADS Biotec's buffer as the mobile phase, high-precision separation can be achieved. Additionally, by following the procedures outlined in the instruction manual and washing the column with 75% acetonitrile, the column can be reused multiple times.

  • High Performance Liquid Chromatograph
  • HPLC columns

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HPLC column "Acclaim Trinity P2 column"

An ideal solution for counterion analysis in pharmaceuticals.

The "Acclaim Trinity P2 Column" is a high-performance silica-based column. It is particularly suitable for HPLC analysis of counter ions in charged pharmaceuticals. The usage is simple, it boasts excellent robustness, and it allows for the analysis of both monovalent and multivalent ions using fast general-purpose methods. Using a general-purpose HPLC, it is possible to effectively analyze counter ions with just one column and one type of analytical method. 【Features】 ■ Effectively analyzes ions using HPLC ■ Enables screening of counter ions present in pharmaceuticals ■ Retains ions or ionic compounds without using ion-pair reagents ■ Simple to use ■ Provides reproducible packing *For more details, please refer to the PDF materials or feel free to contact us.

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[Data] Fully porous 3.5μm HPLC column

Ascentis and Discovery: A rich lineup of stationary phases!

This document introduces the "Ascentis and Discovery All-Porous 3.5μm HPLC Columns." It includes a stationary phase selection guide, usage guide, measurement examples, and a list of HPLC column products. Explanations are provided along with graphs and photos, so please take a moment to read it. [Contents] ■ Stationary Phase Selection Guide ■ Usage Guide ■ Measurement Examples ■ HPLC Column Product List *For more details, please refer to the PDF document or feel free to contact us.

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Oligo analysis HPLC column OligoSep Cartridge

High-performance liquid chromatography (HPLC) column for oligonucleotide analysis

The OligoSep Cartridge manufactured by ADS Biotec (formerly Transgenomic) is a column for oligonucleotide analysis using ion-pair reverse phase HPLC. The packing material consists of non-porous beads made of alkylated polystyrene-divinylbenzene. Due to the non-porous nature of the beads, it allows for higher precision purification. It can be used not only for quality control of oligonucleotides but also for high-precision analysis of both single-stranded and double-stranded DNA. It is compatible with various types of high-performance liquid chromatography (HPLC) systems. By using buffers manufactured by ADS Biotec as the mobile phase, high-precision separation can be achieved. Additionally, by following the procedures outlined in the instruction manual to wash the column with 75% acetonitrile, the column can be reused multiple times.

  • High Performance Liquid Chromatograph
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Fully porous HPLC column

You can easily change the method from a fully porous particle column to a surface porous particle column!

The product features various advantages of fully porous particle columns, such as high retention, load capacity, and solvent resistance. It can be expanded to suit your method, from UHPLC to preparative LC. Additionally, the InfinityLab Poroshell bonded phase is compatible with the traditional ZORBAX bonded phase, allowing for easy method changes from fully porous particle columns to superficially porous particle columns. 【How to choose the appropriate particle for your method (partial)】 ■1.8μm ZORBAX RRHD: Achieves the highest level of performance with UHPLC equipment - Maximum pressure: 1200 bar - Compatible systems: 1290 Infinity II LC or 1260 Infinity II Prime LC ■1.8 ZORBAX RRHT: Ultra-fast chromatography with a maximum of 600 bar - Maximum pressure: 600 bar - Compatible systems: 1260 Infinity II LC *For more details, please refer to the PDF document or feel free to contact us.

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"Cogent TYPE-C Silica" HPLC column

Unique "TYPE-C Silica" used in columns for Cogent HPLC manufactured by MicroSolv in the USA.

The "Cogent TYPE-C column," developed by MicroSolv in the United States, is a next-generation HPLC column based on high-purity Type-B silica that has been modified to replace over 95% of the silanol (Si-OH) on the silica surface with silane (Si-H). By replacing over 95% of the silanol with Si-H, a strong hydrophobic surface is created, providing greater stability compared to traditional silica-based phases. This means that end-capping is not necessary. 【Features】 ■ Usable in three modes in HPLC (RP (reverse phase), NP (normal phase), ANP (aqueous normal phase)) ■ High efficiency and high stability ■ Fast equilibration in gradient ■ Simultaneous separation of polar and non-polar compounds ■ Weak hydration shell *For more details, please refer to the catalog.

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RNA analysis HPLC column "RNASep Prep Column"

High-performance liquid chromatography (HPLC) columns available for research and development of mRNA.

The RNASep Prep column manufactured by ADS Biotec (formerly Transgenomic) in the United States is a column for RNA analysis using high-performance liquid chromatography (HPLC) that can also be used for the research and development of mRNA drugs and mRNA vaccines. The column beads are made from polymer beads, allowing for use over a wider pH range compared to columns with conventional silica beads. It is utilized by customers worldwide, primarily in Europe and the United States.

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mRNA analysis HPLC products RNASep series

Capable of handling everything from mRNA analysis to purification! RNASep series

The RNASep series from ADS Biotec in the United States is capable of handling everything from mRNA analysis to purification.

  • High Performance Liquid Chromatograph
  • HPLC columns

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Inert LC Columns

Improve peak shape without using additives! Achieve high precision and throughput.

We would like to introduce our "Inert LC Column." We offer two products: Raptor Inert Biphenyl HPLC Columns and Raptor Inert ARC-18 HPLC Columns. There is no need for time-consuming conditioning or complex passivation. Additionally, the response and recovery rates of analytes are improved, lowering the detection limits. 【Four Benefits】 ■ Improved peak shape without using passivation or additives in the mobile phase ■ Enhanced response and recovery rates of analytes, resulting in lower detection limits ■ Minimization of variability in analytical results, achieving high precision and throughput ■ Elimination of the need for time-consuming conditioning and complex passivation *For more details, please refer to the PDF document or feel free to contact us.

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ACE C18-AR HPLC Column

Mixed-mode HPLC column integrating C18 and phenyl groups.

This is an HPLC column manufactured by ACT in the UK, featuring a unique selectivity that integrates a phenyl group into a conventional C18 stationary phase. While it is a C18 phase, it exhibits selectivity for aromatic compounds like phenyl groups, providing complementary selectivity when sufficient separation cannot be achieved with C18 alone. **Features:** - A C18-phenyl integrated column that combines the advantages of both C18 phase and phenyl groups. - Utilizes ultra-high purity inert silica, demonstrating excellent peak shape and reproducibility. - Can be used with a water-rich mobile phase that enables retention and separation of polar substances. - Exhibits ultra-low bleed characteristics required for UV/LC-MS. - High-throughput column size.

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Reversed-phase HPLC column "Sunrise C18-SAC"

The reversed-phase HPLC column chemically modified with silanol groups is abbreviated as SAC, which stands for Silanol Activity Control.

The "Sunrise C18-SAC" is an HPLC column that intentionally does not use end-capping, utilizing the properties of residual silanol groups to bond C18. Thanks to silanol activity control technology, it achieves peaks of basic compounds without tailing, even without end-capping. The unique selectivity provided by the regulated silanol groups allows for separations that cannot be achieved with conventional C18 columns. [C18-SAC Octadecyl-SAC] ○ A "2nd Choice" column with effective residual silanol For more details, please contact us or download the catalog.

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ACE C18-PFP HPLC column

HPLC column with pentafluorophenyl (PFP) group bonded to C18 phase.

This is an HPLC column developed by ACT in the UK, combining C18 with a PFP group. By integrating the PFP phase, which provides complementary selectivity to conventional C18, it improves the separation of polar basic substances and demonstrates selective characteristics for halogenated aromatic compounds and positional isomers. Additionally, the C18-PFP phase possesses multiple separation mechanisms (hydrophobic, π-π, hydrogen bonding, shape selectivity), showcasing its capabilities for mixtures that are difficult or impossible to separate with conventional C18. **Features** - A mixed column that combines C18 and PFP (PentaFluoroPhenyl) phases - Enhanced separation capability for polar basic substances - "Ultra-inert & Ultra-pure silica" essential for peak shape and reproducibility - Excellent stability for temperature programming analysis - Optimal for UV and LC/MS due to ultra-low bleed characteristics

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HPLC column "Supel Carbon LC"

Usable at 11,500 psi! Porous graphite carbon HPLC column

"Supel Carbon LC" is a porous graphite carbon HPLC column suitable for the separation of water-soluble analog compounds. The maximum operating temperature is 250°C, and it is compatible with pH 1 to 14. It is effective for the separation of hydrophilic analog compounds. Patented porous graphite carbon (PGC) particles are used as the packing material. 【Features】 ■ For the separation of water-soluble analog compounds ■ Can be backwashed ■ Compatible with pH 1 to 14 ■ Maximum operating temperature of 250°C ■ Usable at 11,500 psi (800 bar) *For more details, please refer to the PDF document or feel free to contact us.

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ACE UltraCore UHPLC·HPLC Column

Solid core (core-shell) particles appear in the ACE column! Unique EBT technology achieves high stability across a wide pH range.

A new UltraCore column (HPLC/UHPLC column) has been added, featuring solid core (surface porous) particles from the UK ACE column group. Compared to conventional fully porous silica, it can be used at lower pressures, and due to the limited diffusion of analytes, it achieves high efficiency and sharp peak shapes. Additionally, it employs a unique encapsulation bonding technology (EBT) that delivers stable high performance across a wide pH range, dramatically increasing the ligand coverage on the silica surface and effectively eliminating the negative effects of unbound silanols. **Features** - Utilizes ultra-inert solid core particles (surface porous) - Monodisperse particle distribution combining low pressure and high efficiency - Expanded pH stability (1.5 to 11.0) - Compatible with LC/MS buffers - Employs unique encapsulation bonding technology (EBT)

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HPLC column "SunArmor"

Further evolution of surface treatment! HPLC columns that achieve astonishing alkali resistance.

"SunArmor" is an HPLC column that achieves remarkable alkali resistance while being silica gel particles, thanks to the newly developed silylation agent and TMS for final end-capping, in addition to the conventional Sunniest end-capping. The usable pH range of the mobile phase with the C18 stationary phase is from 2 to 12, providing durability equivalent to hybrid silica. A high-durability NH2 column has been added. 【Features】 ○ Superior alkali resistance compared to other hybrid C18 columns ○ Not affected by residual silanol groups ○ Exhibits good peak shapes for acidic, basic, and metal-coordinating compounds For more details, please contact us or download the catalog.

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ACE SuperC18 UHPLC & HPLC Column

SuperC18 UHPLC/HPLC column with expanded pH range due to unique encapsulation technology.

The ACE SuperC18 column is a UHPLC/HPLC column that expands the usable pH range (pH 1.5 to 11.5) compared to conventional C18 columns, thanks to the unique EBT technology (Encapsulated Bonding Technology) developed by ACT (Advanced Chromatography Technologies). The unique EBT technology dramatically increases the ligand coverage on the silica surface, eliminating the influence of unbound silanols, thereby enhancing inertness and stability. It is also designed for use with LC-MS buffers, providing ultra-low bleed to improve compatibility with LC-MS. It can be used with both methanol and acetonitrile as mobile phases, offering rapid column equilibration without memory effects. **Features** - Selectivity changes are available (in low, medium, and high pH ranges) - Excellent column life reduces costs - Usable with LC/MS compatible buffers - Recommended pH range: 1.5 to 11.5 - Compatibility with both methanol and acetonitrile - Fast column equilibration without memory effects

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ZORBAX Original Reverse Phase HPLC Column

It has a high activity level and helps in the separation of isomers and the improvement of selectivity!

We would like to introduce the "ZORBAX Original Reverse Phase HPLC Column" that we handle. Our lineup includes "ZORBAX C18," "ZORBAX C8," "ZORBAX-Phenyl," and others. These columns are manufactured using Type A silica and are useful for the separation of acidic or neutral compounds. Please feel free to consult us when you need assistance. 【ZORBAX C18 Specifications】 ■ZORBAX C18 - Pore Size: 70A - Surface Area: 300m²/g - Temperature Range: 60℃ - pH Range: 2.0-8.0 - End Cap: Yes - Carbon Content: 20% *For more details, please refer to the PDF document or feel free to contact us.

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[Data] RP-Amide HPLC/UHPLC Column

Improvement of retention for carboxylic acids and phenolic compounds! Achieving low bleed suitable for LC-MS applications.

This document provides an explanation of "RP-Amide HPLC/UHPLC columns." It introduces the "characteristics of RP-Amide," the "differences in retention for neutral analytes," and the "increased retention for hydrogen bond donors." Additionally, it includes analyses of "ulcer medications using Ascentis RP-Amide" and "UHPLC measurements of sunscreen drugs using Ascentis Express RP-Amide, 2.7μm." We encourage you to read it. 【Contents】 ■Ascentis RP-Amide HPLC column ■Analysis of ulcer medications using Ascentis RP-Amide ■UHPLC measurements of sunscreen drugs using Ascentis Express RP-Amide, 2.7μm ■Data sheet on the care and use of Ascentis Express RP-Amide columns ■LC/MS workflow products ■Ascentis RP-Amide product list ■Fused-Core product list *For more details, please refer to the PDF document or feel free to contact us.

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HPLC column

A lineup of HPLC columns that achieves outstanding chromatography.

Waters is developing a business based on chromatography. It is our customers who utilize this chromatography technology in their businesses. The innovative insights in your labs lead to the establishment of analytical/testing methods that contribute to business success. Our customers' "success" can be evaluated by continuously monitoring analytical methods and results, and it is essential that the chosen columns remain available for you to continue achieving "success" in the future. Many customers who fully understand the impact of column performance and innovation on "success" have chosen Waters' cutting-edge reversed-phase and HILIC HPLC column products. 【Features】 - Synthesis of silica and hybrid materials conducted in-house: Latest technology can be applied to particles. - All latest chromatography packing materials are consistently managed from starting monomers to final products. - Manufacturing facilities are certified cGMP, ISO9001, and ISO13485: Establishing analytical reliability through stringent quality control systems. - Most column hardware is also manufactured in-house from raw materials. - As a global company, we provide products of the same quality in countries around the world.

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Silica-based column for HPLC/UHPLC "ACE Column"

High efficiency and high separation capability based on ultra-inactive silica. With a wide range of sizes and a rich lineup of bonding phases, we lead difficult separations to success.

Our company offers the 'ACE Columns' for HPLC/UHPLC, which are highly regarded for their reliability in countries around the world. Based on ultra-high purity silica, we have a range of products from the representative C18 type to various chemically modified options, with a rich lineup of gel particle sizes and column sizes. We achieve high efficiency, high separation capability, and long lifespan, making our columns recommended for those who are not obtaining desirable analytical results with their current columns or who wish to reduce column costs. 【Features】 - Uses ultra-high purity and inert silica - Available in particle sizes of 3, 5, 10, and 15 μm - Excellent reproducibility due to strict quality control - Theoretical plate number of over 200,000 plates/m - Available pore sizes of 100Å and 300Å - Various guard cartridge columns are also available to extend column lifespan *For more details, please refer to the PDF document (English version) or feel free to contact us.

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[Technical Data] Quality characteristic analysis of antibody drugs is settled with this!

The analysis of quality characteristics of antibody drugs is settled with this! For the analysis of important quality characteristics of antibody drugs!

The identification of critical quality attributes (CQAs) of antibody drugs, the establishment of their management scope, and their analysis can be effectively achieved using HPLC/UHPLC. We will introduce the TSKgel series (columns) used in the analysis of critical quality attributes and risk assessment of antibody drugs with UHPLC/HPLC.

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